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phenobarbital will reduce the level or impact of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Solid or moderate CYP3A4 inducers could improve level of diazepam elimination; for that reason, efficacy of diazepam could possibly be reduced.Barbiturates tend not to impair standard hepatic perform